Inhibition of Ca ̄(2+)/CaM PKⅡ Autophosphorylation Induced by Cerebral Ischemia;
脑缺血诱导Ca~(2+)/CaM依赖性蛋白激酶Ⅱ自(身)磷酸化的抑制作用
However, the role of autophosphorylation of Hsp70 and its effects on the chaperone function have not been elucidated.
有报道认为,Hsp70蛋白的NDP激酶样作用,通过形成酸不稳定性自(身)磷酸化中间体催化γ-磷酸基团在ATP和ADP间传递,组氨酸H89与这个新的区域有密切关系,有可能与Hsp70蛋白形成自(身)磷酸化中间体有关。
The extent increase of Ca2+/CaM-dependent protein kinase Ⅱ (CaMK Ⅱ)autophosphorylation in various brain regions of rat reached a maximum value, one hour after s.
大鼠皮下注射加压素(AVP)(4-8)1h后,大脑皮层中Ca2+/CaM依赖的蛋白激酶Ⅱ(CaMKⅡ)自(身)磷酸化程度与对照组比较增高192%,P<0。
By using an autophosphorylation assay of proteinkinases that had been separated from other proteins by SDS-PAGE and blotted onto PVDF membranes (Ferrell and Martin 1991 ), combined with in vitro prephosphorylation of the samples with,unlabelled ATP, we studied the in vitro autophosphorylation characteristics of soybean primary .
利用Ferrell和Martin(1991)设计的测定印迹在PVDF膜上的蛋白激酶活性方法研究大豆叶片质膜蛋白激酶自(身)磷酸化反应活性,结果表明:与Mg-ATP相比,Mn-ATP是更有效的57KD蛋白激酶自(身)磷酸化反应底物;钙离子可以促进该激酶的自(身)磷酸化反应活性,而且EGTA可以显著降低它在SDS电泳中的迁移率,说明57KD蛋白激酶为依赖于钙的蛋白激酶;预磷酸化反应实验证明57KD蛋白激酶具有多个自(身)磷酸化反应位点,其分子的自(身)磷酸化状态可调性暗示这一激酶可能具有重要的生理功能。
The first is " zi" in the sentence "There s a fine girl in neighbour named Qin Luo -fu", which means "originally" as an adverb.
第一,在“东家有贤女,自名秦罗敷”中,“自”应作副词“本来”讲。
Du Fu tends to employ “ego” since the word makes more than 360 appea rances in the book The Detailed Notes of Du Fu′s Poems.
杜甫好言“自”字,一部《杜诗详注》,该字出现了360多处。
Organic matter heterogeneity was counted and studied for the fractured "in situ reservoir" samples of upper Permian series in Malang sag Santanghu basin.
三塘湖盆地马朗凹陷上二叠统芦草沟组油藏多为"自生自储"裂缝型油藏,油藏样品的实验分析揭示了油藏宏观、微观两种尺度上的"有机质"非均质性表现;通过对油藏非均质性表现的成因分析,认为该类裂缝型油藏的有效油气储存空间主要是各级裂缝及毗邻基质孔隙;结合油藏特殊构造、沉积、成岩演化及烃源岩生烃演化等地质条件,探讨了该类"自生自储"裂缝油藏的油气聚集、成藏机制—"源内排烃"模式。
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