The small monomeric G protein Ran has GTPase activity, its bound conformation Ran-GTP might act as a molecular marker that distinguishes the nucleoplasm from the cytoplasm of interphase cells, and plays different roles in nucleocytoplasmic transport, mitotic spindle assembly and nuclear envelope dynamics.
现就Ran在真核细胞核质运输、有丝分裂纺锤体组装与核膜动力学中的功能作一综述。
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