endogenous morphine-like peptides是什么意思

网络释义

用法例句

Effect of Endomorphin on Contractile Response of Colon Muscle Strips in Cathartic Colon Rats in Vitro;

内吗啡肽对“泻剂结肠”大鼠离体肠肌条收缩反应的影响

Influence of intracerebroventricular administraction of endomorphine-1 on left venteicular systolic pressuer in rats;

侧脑室注射内吗啡肽-1对大鼠心功能的影响

Analgesic mechanism of endomorphin in the superficial laminae of the spinal dorsal horn;

内吗啡肽在脊髓背角浅层的镇痛机制

Development of Potent Endomorphins Analogs Using Atypical Conformationally Constrained C-Terminus and Characterization of Opioid Activities of Endomorphins and Their Analogs Both in Vivo and in Vitro;

C-末端空间立体构象限制的内吗啡肽的构建以及内吗啡肽及其类似物的生理、药理活性研究

Structure-activity Relationships of the Novel Dimeric, Side Chain and C-terminal Modified Analogs of Endomorphins;

二聚化以及侧链和碳末端修饰的内吗啡肽类似物的构效关系研究

Alterations of the Regulatory Function of Endomorphins on the Cardiovascular System and Bronchoconstriction in Type I Diabetes;

糖尿病病理状态下内吗啡肽对心血管系统及支气管收缩调节功能的变化

Endomorphins including endomorphin-1(H-Tyr-Pro-Trp-Phe-NH_2, EM1) andendomorphin-2(H-Tyr-Pro-Phe-Phe-NH_2, EM2) were discovered, isolated anddemonstrated to have high selectivity and affinity forμ-opioid receptors in 1997.

内吗啡肽是一种具有吗啡活性的内源性四肽，包括内吗啡肽-1(H-Tyr-Pro-Trp-Phe-NH_2)和内吗啡肽-2(H-Tyr-Pro-Phe-Phe-NH_2)。

The tetrapeptide of endomorphin-2, a strong agonist of the u-acceptor with high affinity and selectivity, was synthesized from L-tyrosine、 L-proline and L-phenylalanine by liquid phase condensation.

采用先合成两个二肽片段，再合成四肽的合成策略，以酪氨酸(L-Tyr)、脯氨酸(L-Pro)、苯丙氨酸(L-Phe)为起始原料，液相条件下合成出内吗啡肽-2(endomorphin-2，H-Tyr-Pro-Phe-Phe-NH_2)三氟乙酸盐。

Two potent endogenous opioid peptides,endomorphin-1(EM1;H-Tyr-Pro-Trp-Phe-NH_2) and endomorphin-2(EM2;H-Tyr-Pro-Phe-Phe-NH_2),which showed high affinity and selectivity toward theμ-opioid receptor,were isolated from bovine brain in 1997.

1997年,内吗啡肽-1(H-Tyr-ProTrp-Phe-NH_2)和内吗啡肽-2(H-Tyr-Pro-Phe-Phe-NH_2)从牛脑中分离提纯得到,它们是对μ-阿片受体具有高亲和性和选择性的内源性阿片肽。

CoMFA Studies of Endomorphin-2 Analogues;

内吗啡肽2类似物的CoMFA研究

Finally,the research of cerebral morphia peptide will deepen our understanding to aesthetic education.

三是脑内吗啡肽的研究对美育作用认识的深化。

Synthesis and Analgesic Activities of Endomorphin-2 and Its Analogues;

内吗啡肽-2及其类似物的合成与镇痛活性研究

An Experimental Study on EM-1 Inducing K562 Cell Apoptosis;

内吗啡肽-1诱导K562细胞凋亡的实验研究

Study the Brain-targeting Nanoparticles of HDAPC, an Analog of EM-1

内吗啡肽-1类似物HDAPC的脑靶向纳米粒研究

Pharmacological Study on Endogenous Opioid Peptide (Endomorphins) and Natural Polyphenol Compound (Caffeic Acid Phenethyl Ester);

内源性阿片肽内吗啡肽与天然多酚类化合物咖啡酸苯乙酯的药理学活性研究

Analgesic Effects of Spinal Endomorphine on Peripheral Inflammation--Behavioral Study;

内吗啡肽在炎性痛动物脊髓内镇痛作用的行为学观察

Studies of the in Vivo Antioxidant Properties and the in Vitro Oxidative Metabolites of Endomorphins

内吗啡肽体内抗氧化活性及其体外氧化代谢产物的研究

Structure-activity Relationships of the Novel Dimeric, Side Chain and C-terminal Modified Analogs of Endomorphins;

二聚化以及侧链和碳末端修饰的内吗啡肽类似物的构效关系研究

Synthesis and Pharmacological Activity of Novel Endomorphin-1 Analogues with Combined Chemical Modification;

组合化学修饰内吗啡肽-1类似物的合成和药理学活性研究

Analgesis, Addiction Studies and Molecular Modelling of Three Endomorphin Analogs;

三种内吗啡肽类似物的镇痛和成瘾性研究及分子模拟

The Reciprocal Connections of Endomorphin 1-and Endomorphin 2-containing Neurons between the Hypothalamus and Nucleus Tractus Solitarii in the Rat;

大鼠下丘脑与孤束核间内吗啡肽阳性神经元的往返联系

The Mechanism Underlying the Regulation of Endomorphins on the Periphery Nociceptive Information Transmission in the Superficial Laminae of the Rat Spinal Dorsal Horn;

内吗啡肽在大鼠脊髓背角浅层调控外周伤害性信息传递的机制

The Regulatory Effects of Endomorphins, Morphiceptin and Their Analogs on Mouse Colonic Motility;

内吗啡肽、morphiceptin及其类似物对小鼠结肠运动功能的调节作用

Type 1 Diabetes Alters the Modulatory Effects of Endomorphins on Mouse Colonic Motility

Ⅰ型糖尿病改变了内吗啡肽对小鼠结肠收缩特性的影响

EM-1's Influence on the Hemopoiesis Control of the Bone Marrow Stromal Cell

内吗啡肽-1对正常骨髓基质细胞造血调控的影响

Analgesic activity of polybutylcyanoacrylate nanoparticles of HDAPC,an analog of Endomorphin-1

内吗啡肽-1类似物HDAPC聚氰基丙烯酸正丁酯纳米粒的镇痛活性

Modification of Endomorphin-1 to Enhance the Blood-brain Barrier Permeability: Design, Synthesis and Biological Activity Characterization;

内吗啡肽-1衍生多肽的设计合成、生物学活性及血脑屏障通透性研究